Pub. Date : 2003 Dec
PMID : 14675200
6 Functional Relationships(s)Download |
Sentence | Compound Name | Protein Name | Organism |
| 1 | Aquaporin 3 is a channel that transports both water and glycerol. | Glycerol | aquaporin 3 | Mus musculus |
| 2 | Aquaporin 3-deficient mice exhibit skin defects, including decreased glycerol content and impairment of water holding capacity, barrier recovery, and wound healing. | Glycerol | aquaporin 3 | Mus musculus |
| 3 | Whether aquaporin 3 and its glycerol transporting capacity are involved in regulating keratinocyte function, we have previously shown that phospholipase D2 can metabolize phospholipids in the presence of glycerol to yield phosphatidylglycerol. | Glycerol | aquaporin 3 | Mus musculus |
| 4 | In addition, aquaporin 3 expression was downregulated at the transcriptional level and glycerol uptake was reduced upon primary mouse keratinocytes to differentiation in response to an elevated extracellular calcium concentration or 1,25-dihydroxyvitamin D3. | Glycerol | aquaporin 3 | Mus musculus |
| 5 | Our results suggest that aquaporin 3 and phospholipase D2 form a signaling module in lipid rafts, where aquaporin 3 transports glycerol to phospholipase D2 for the synthesis of phosphatidylglycerol. | Glycerol | aquaporin 3 | Mus musculus |
| 6 | Our results suggest that aquaporin 3 and phospholipase D2 form a signaling module in lipid rafts, where aquaporin 3 transports glycerol to phospholipase D2 for the synthesis of phosphatidylglycerol. | Glycerol | aquaporin 3 | Mus musculus |