Title : Arsenite and arsenate activate extracellular signal-regulated kinases 1/2 by an epidermal growth factor receptor-mediated pathway in normal human keratinocytes.

Pub. Date : 2003 Dec

PMID : 14674888






1 Functional Relationships(s)
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1 Both the EGFR inhibitor tyrphostin AG1478 and anti-EGFR blocking antibody markedly attenuated ERK1/2 activation induced by arsenicals, but did not affect JNK and p38 activation. Tyrphostins epidermal growth factor receptor Homo sapiens