Title : Herbal bioactivation: the good, the bad and the ugly.

Pub. Date : 2004 Jan 9

PMID : 14672753






1 Functional Relationships(s)
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Sentence
Compound Name
Protein Name
Organism
1 Extensive pulegone metabolism generated p-cresol that was a glutathione depletory, and the furan ring of the diterpenoids in germander was oxidized by CYP3A4 to reactive epoxide which reacts with proteins such as CYP3A and epoxide hydrolase. Epoxy Compounds cytochrome P450 family 3 subfamily A member 4 Homo sapiens