Title : Characterization and modulation of sex steroid metabolizing activity in normal human keratinocytes in primary culture and HaCaT cells.

Pub. Date : 2003 Nov

PMID : 14672737






1 Functional Relationships(s)
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1 In this regard, we found that interleukin-4 (IL-4) induced the expression of 3beta-HSD in HaCaT cells, thus allowing the cells to produce a different set of sex steroids from adrenal C19 precursors. Steroids hydroxy-delta-5-steroid dehydrogenase, 3 beta- and steroid delta-isomerase 1 Homo sapiens