Title : Costunolide inhibits interleukin-1beta expression by down-regulation of AP-1 and MAPK activity in LPS-stimulated RAW 264.7 cells.

Pub. Date : 2004 Jan 2

PMID : 14672714






1 Functional Relationships(s)
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1 Additionally, specific inhibitors of SAPK/JNK and p38 MAP kinase, SP600125 and SB203580, also suppressed LPS-induced increase in IL-1beta gene expression and AP-1 DNA binding. SB 203580 interleukin 1 beta Mus musculus