Title : Cell-cycle gene expression in lovastatin-induced medulloblastoma apoptosis.

Pub. Date : 2003 Nov

PMID : 14672267






3 Functional Relationships(s)
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1 4) Following lovastatin treatment, increased p53 protein is detected only in D341 Med, and bax protein is unchanged in all cell lines. Lovastatin tumor protein p53 Homo sapiens
2 Lovastatin-induced apoptosis in medulloblastoma is probably p53 independent, but p53 and p21WAF1 gene expression may also mediate anti-proliferative effects of lovastatin on specific medulloblastoma cell lines. Lovastatin tumor protein p53 Homo sapiens
3 Lovastatin-induced apoptosis in medulloblastoma is probably p53 independent, but p53 and p21WAF1 gene expression may also mediate anti-proliferative effects of lovastatin on specific medulloblastoma cell lines. Lovastatin tumor protein p53 Homo sapiens