Title : A role for the androgen receptor in the endometrial antiproliferative effects of progesterone antagonists.

Pub. Date : 2003 Nov

PMID : 14667996






5 Functional Relationships(s)
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1 A role for the androgen receptor in the endometrial antiproliferative effects of progesterone antagonists. Progesterone androgen receptor Homo sapiens
2 Recent studies of ours in both women and macaques revealed that the endometrial androgen receptor (AR) was increased by progesterone antagonist treatment. Progesterone androgen receptor Homo sapiens
3 Recent studies of ours in both women and macaques revealed that the endometrial androgen receptor (AR) was increased by progesterone antagonist treatment. Progesterone androgen receptor Homo sapiens
4 Because androgens are known to suppress estrogen-dependent endometrial proliferation, we hypothesized that the AR was involved in the antiproliferative effects induced by progesterone antagonists. Progesterone androgen receptor Homo sapiens
5 These data implicate the AR as a functional component of the mechanism through which progesterone antagonists induce endometrial antiproliferative effects in the presence of estrogens. Progesterone androgen receptor Homo sapiens