Pub. Date : 2003 Nov
PMID : 14667967
3 Functional Relationships(s)Download |
Sentence | Compound Name | Protein Name | Organism |
| 1 | Progesterone-dependent regulation of female reproductive activity by two distinct progesterone receptor isoforms. | Progesterone | progesterone receptor | Mus musculus |
| 2 | More recently, selective ablation of the PR-A and PR-B proteins in mice had facilitated examination of the contribution of the individual PR isoforms to the pleiotropic reproductive activities of progesterone. | Progesterone | progesterone receptor | Mus musculus |
| 3 | Analysis of the phenotypic consequences of these mutations on female reproductive function has provided proof of concept that the distinct transcriptional responses to PR-A and PR-B observed in cell-based transactivation assays are reflected in a distinct tissue-selective contribution of the individual isoforms to the reproductive activities of progesterone. | Progesterone | progesterone receptor | Mus musculus |