Pub. Date : 2004 Jan
PMID : 14662725
5 Functional Relationships(s)Download |
Sentence | Compound Name | Protein Name | Organism |
| 1 | We here evaluated the early kinetic of SCF expression regulated by interleukin (IL)-1beta, budesonide and the combination of both in human lung fibroblasts in culture. | Budesonide | KIT ligand | Homo sapiens |
| 2 | Budesonide potentiated the IL-1beta-enhanced expression of SCF mRNA (+103%) and protein (+98%) very shortly after treatment (at 30 min and 1 h, respectively). | Budesonide | KIT ligand | Homo sapiens |
| 3 | This potentiating effect of budesonide was related to increased SCF mRNA stability and SCF gene transcription. | Budesonide | KIT ligand | Homo sapiens |
| 4 | This potentiating effect of budesonide was related to increased SCF mRNA stability and SCF gene transcription. | Budesonide | KIT ligand | Homo sapiens |
| 5 | Deletion of a kappaB-like site that we identified in the first intron of the SCF gene, in a luciferase reporter system, abolished the potentiation by budesonide, as well as the effect of IL-1beta alone, as compared to the wild-type construction activity. | Budesonide | KIT ligand | Homo sapiens |