Pub. Date : 2003 Dec
PMID : 14660711
7 Functional Relationships(s)Download |
Sentence | Compound Name | Protein Name | Organism |
| 1 | UNLABELLED: The changes in cerebral blood flow (CBF) and arterial-to-capillary blood volume (V(0)) induced by acetazolamide (ACZ) are expected to be parallel each other in the normal circulation; however, it has not been proven that the same changes in those parameters are observed in patients with cerebrovascular disease. | Acetazolamide | CCAAT/enhancer binding protein zeta | Rattus norvegicus |
| 2 | UNLABELLED: The changes in cerebral blood flow (CBF) and arterial-to-capillary blood volume (V(0)) induced by acetazolamide (ACZ) are expected to be parallel each other in the normal circulation; however, it has not been proven that the same changes in those parameters are observed in patients with cerebrovascular disease. | Acetazolamide | CCAAT/enhancer binding protein zeta | Rattus norvegicus |
| 3 | RESULTS: The regional CBF (rCBF) and V(0) increased significantly after ACZ administration in the hemisphere contralateral to the ischemic side. | Acetazolamide | CCAAT/enhancer binding protein zeta | Rattus norvegicus |
| 4 | RESULTS: The regional CBF (rCBF) and V(0) increased significantly after ACZ administration in the hemisphere contralateral to the ischemic side. | Acetazolamide | CCAAT/enhancer binding protein zeta | Rattus norvegicus |
| 5 | A parameter defined by the rCBF/V(0) ratio decreased significantly in the ipsilateral hemisphere of group A after ACZ administration, although the ratio showed no change in the contralateral hemisphere or in the other subgroup (group B). | Acetazolamide | CCAAT/enhancer binding protein zeta | Rattus norvegicus |
| 6 | CONCLUSION: The change in the rCBF/V(0) ratio after ACZ challenge may represent an alteration in arterial perfusion pressure that is expected to indicate a critical hemodynamic status in patients with cerebrovascular disease, especially in patients who have a reduced rCBF response. | Acetazolamide | CCAAT/enhancer binding protein zeta | Rattus norvegicus |
| 7 | CONCLUSION: The change in the rCBF/V(0) ratio after ACZ challenge may represent an alteration in arterial perfusion pressure that is expected to indicate a critical hemodynamic status in patients with cerebrovascular disease, especially in patients who have a reduced rCBF response. | Acetazolamide | CCAAT/enhancer binding protein zeta | Rattus norvegicus |