Title : Phosphoinositide 3-kinase-mediated activation of cofilin phosphatase Slingshot and its role for insulin-induced membrane protrusion.

Pub. Date : 2004 Feb 20

PMID : 14645219






2 Functional Relationships(s)
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Sentence
Compound Name
Protein Name
Organism
1 Cofilin is inactivated by phosphorylation at Ser-3 by LIM kinase and reactivated by dephosphorylation by cofilin-phosphatase Slingshot (SSH). Serine cofilin 1 Homo sapiens
2 Consistent with this, the level of Ser-3-phosphorylated cofilin is increased in PTEN (phosphatase and tensin homolog deleted in chromosome 10)-overexpressing cells and decreased in PTEN-deficient cells. Serine cofilin 1 Homo sapiens