Pub. Date : 2003 Dec
PMID : 14644129
3 Functional Relationships(s)Download |
Sentence | Compound Name | Protein Name | Organism |
| 1 | By using in vitro cell invasion assay system, we evaluated the effects of amiloride and urinary trypsin inhibitor (UTI), which inhibit uPA and plasmin, respectively, on invasion by both cell lines. | Amiloride | plasminogen | Homo sapiens |
| 2 | Amiloride and UTI significantly inhibited plasmin formation and the invasion of both cell lines (p<0.001). | Amiloride | plasminogen | Homo sapiens |
| 3 | Thus, inhibitors of uPA and plasmin, such as amiloride and UTI, respectively, could be useful therapeutic tools with which to treat urothelial cancer. | Amiloride | plasminogen | Homo sapiens |