Pub. Date : 2004
PMID : 14643170
4 Functional Relationships(s)Download |
Sentence | Compound Name | Protein Name | Organism |
| 1 | This study was performed to investigate the effectiveness of the commonly used steroids beclomethasone, budesonide and fluticasone in downregulating HASMC production of RANTES and IL-8. | Budesonide | C-X-C motif chemokine ligand 8 | Homo sapiens |
| 2 | Pre-treatment with beclomethasone, budesonide or fluticasone reduced TNFalpha- and IL-1beta-stimulated IL-8 and RANTES release from HASMC in a dose dependent manner. | Budesonide | C-X-C motif chemokine ligand 8 | Homo sapiens |
| 3 | TNFalpha- and IL-1beta-induced RANTES and IL-8 expression was reduced on the transcriptional level by pre-treatment with fluticasone and budesonide. | Budesonide | C-X-C motif chemokine ligand 8 | Homo sapiens |
| 4 | The results suggest that the topical steroids fluticasone, budesonide and to a lesser extent beclomethasone may have beneficial effects on airway inflammation in asthma by reducing RANTES and IL-8-induced leukocyte infiltration into the airway wall. | Budesonide | C-X-C motif chemokine ligand 8 | Homo sapiens |