Title : Polymeric IgA1 from patients with IgA nephropathy upregulates transforming growth factor-beta synthesis and signal transduction in human mesangial cells via the renin-angiotensin system.

Pub. Date : 2003 Dec

PMID : 14638911






1 Functional Relationships(s)
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1 When similar experiments were performed with the addition of either captopril or losartan, there was a significant increase in the renin gene expression by HMC, whereas the synthesis of TGF-beta was markedly reduced. Captopril renin Homo sapiens