Pub. Date : 2003 Dec 9
PMID : 14634213
2 Functional Relationships(s)Download |
Sentence | Compound Name | Protein Name | Organism |
1 | We now show that, like dicoumarol, several other coumarin and flavone inhibitors of NQO1 activity, which compete with NAD(P)H for binding to NQO1, induced ubiquitin-independent p53 degradation and inhibited wild-type p53-mediated apoptosis. | coumarin | tumor protein p53 | Homo sapiens |
2 | We now show that, like dicoumarol, several other coumarin and flavone inhibitors of NQO1 activity, which compete with NAD(P)H for binding to NQO1, induced ubiquitin-independent p53 degradation and inhibited wild-type p53-mediated apoptosis. | coumarin | tumor protein p53 | Homo sapiens |