Title : Acute ethanol exposure inhibits macrophage IL-6 production: role of p38 and ERK1/2 MAPK.

Pub. Date : 2004 Mar

PMID : 14634061






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1 Acute ethanol exposure inhibits macrophage IL-6 production: role of p38 and ERK1/2 MAPK. Ethanol interleukin 6 Homo sapiens
2 We demonstrated that a single dose of ethanol transiently down-regulated p38 and ERK1/2 activation levels (3-24 h after treatment) and impaired IL-6 synthesis. Ethanol interleukin 6 Homo sapiens
3 These results demonstrate that acute ethanol exposure can impair macrophage IL-6 production and indicate that this effect may result from ethanol-induced alterations in intracellular signaling through p38 and ERK1/2. Ethanol interleukin 6 Homo sapiens
4 These results demonstrate that acute ethanol exposure can impair macrophage IL-6 production and indicate that this effect may result from ethanol-induced alterations in intracellular signaling through p38 and ERK1/2. Ethanol interleukin 6 Homo sapiens