Title : Differential role of p38 in IL-1alpha induction of MMP-9 and MMP-13 in an established liver myofibroblast cell line.

Pub. Date : 2003 Nov-Dec

PMID : 14631115






2 Functional Relationships(s)
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1 Recombinant IL-1alpha upregulated the expression of both MMP-9 and -13, and the induction of MMP-13 but not MMP-9 could be inhibited by SB203580, an inhibitor of p38. SB 203580 interleukin 1 alpha Homo sapiens
2 Similarly, in primarily cultured human liver MFs, upregulation of MMP-1 by IL-1alpha was also shown to be inhibited by SB203580. SB 203580 interleukin 1 alpha Homo sapiens