Pub. Date : 2004 Mar 15
PMID : 14630830
3 Functional Relationships(s)Download |
Sentence | Compound Name | Protein Name | Organism |
| 1 | The promyelocytic leukemia (PML) tumor suppressor of acute promyelocytic leukemia (APL) is essential for a number of proapoptotic and growth-suppressive pathways as well as for the activity of differentiating agents such as retinoic acid (RA). | Tretinoin | PML nuclear body scaffold | Homo sapiens |
| 2 | The promyelocytic leukemia (PML) tumor suppressor of acute promyelocytic leukemia (APL) is essential for a number of proapoptotic and growth-suppressive pathways as well as for the activity of differentiating agents such as retinoic acid (RA). | Tretinoin | PML nuclear body scaffold | Homo sapiens |
| 3 | Complete functional loss of PML is therefore selected by the APL phenotype and associates with poor prognosis and RA unresponsiveness. | Tretinoin | PML nuclear body scaffold | Homo sapiens |