Pub. Date : 2003 Dec
PMID : 14630342
2 Functional Relationships(s)Download |
Sentence | Compound Name | Protein Name | Organism |
| 1 | PC12 cells undergo neuritogenesis upon nerve growth factor (NGF) activation of the TrkA receptor, an effect mimicked by the ganglioside GM1 binding B-subunit of cholera toxin (CTB). | G(M1) Ganglioside | neurotrophic receptor tyrosine kinase 1 | Homo sapiens |
| 2 | These data indicate that GM1/ligand interaction does not necessarily lead to neuritogenesis and suggest that a specialisation of CTB, not shared by anti-GM1 antibodies or rETxB, is required to activate TrkA. | G(M1) Ganglioside | neurotrophic receptor tyrosine kinase 1 | Homo sapiens |