Title : Central cyclooxygenase-2 participates in interleukin-1 beta-induced hyperalgesia in the orofacial formalin test of freely moving rats.

Pub. Date : 2003 Dec 11

PMID : 14625016






1 Functional Relationships(s)
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1 Pretreatment with indomethacin, a non-selective COX inhibitor, or NS-398, a selective COX-2 inhibitor, blocked IL-1beta-induced hyperalgesic responses. N-(2-cyclohexyloxy-4-nitrophenyl)methanesulfonamide interleukin 1 beta Rattus norvegicus