Pub. Date : 2003 Aug
PMID : 14624028
5 Functional Relationships(s)Download |
Sentence | Compound Name | Protein Name | Organism |
| 1 | Indeed, folate deprivation, which has been associated with AD, potentiates generation of reactive oxygen species (ROS) by Abeta. | Folic Acid | amyloid beta precursor protein | Homo sapiens |
| 2 | Folate-deprivation and Abeta treatment each induced an increase in ROS, and treatment of folate-deprived cultures with Abeta induced a synergistic increase in ROS. | Folic Acid | amyloid beta precursor protein | Homo sapiens |
| 3 | 17-beta-estradiol reduced ROS levels in beta-treated, folate-deprived cultures to ROS levels observed in cultures treated with Abeta in the presence of folate, suggesting that this antioxidant was able to prevent the synergistic impact of Abeta and folate deprivation on ROS generation. | Folic Acid | amyloid beta precursor protein | Homo sapiens |
| 4 | 17-beta-estradiol reduced ROS levels in beta-treated, folate-deprived cultures to ROS levels observed in cultures treated with Abeta in the presence of folate, suggesting that this antioxidant was able to prevent the synergistic impact of Abeta and folate deprivation on ROS generation. | Folic Acid | amyloid beta precursor protein | Homo sapiens |
| 5 | 17-beta-estradiol reduced ROS levels in beta-treated, folate-deprived cultures to ROS levels observed in cultures treated with Abeta in the presence of folate, suggesting that this antioxidant was able to prevent the synergistic impact of Abeta and folate deprivation on ROS generation. | Folic Acid | amyloid beta precursor protein | Homo sapiens |