Pub. Date : 2003 Nov 28
PMID : 14623295
2 Functional Relationships(s)Download |
Sentence | Compound Name | Protein Name | Organism |
| 1 | The crystal structures of CN and its complexes with FKBP12-FK506 and cyclophilin-cyclosporin showed that the two structurally unrelated immunophilins-immunosuppressants bind to a common composite surface made up of the residues from both catalytic subunit and regulatory subunit of CN. | Tacrolimus | FKBP prolyl isomerase 1A pseudogene 4 | Homo sapiens |
| 2 | However, the binding pattern of FKBP12-FK506 such as hydrogen bonding is significantly different from that of CyPA-CsA. | Tacrolimus | FKBP prolyl isomerase 1A pseudogene 4 | Homo sapiens |