Pub. Date : 2003 Nov 28
PMID : 14623285
8 Functional Relationships(s)Download |
Sentence | Compound Name | Protein Name | Organism |
| 1 | The synergistic activation of Raf-1 kinase by phorbol myristate acetate and hydrogen peroxide in NIH3T3 cells. | Tetradecanoylphorbol Acetate | v-raf-leukemia viral oncogene 1 | Mus musculus |
| 2 | We have previously demonstrated that a 33kDa C-terminal fragment of c-Raf-1 underwent a mobility shift in response to hydrogen peroxide (H(2)O(2)) and phorbol myristate acetate (PMA), respectively. | Tetradecanoylphorbol Acetate | v-raf-leukemia viral oncogene 1 | Mus musculus |
| 3 | We have previously demonstrated that a 33kDa C-terminal fragment of c-Raf-1 underwent a mobility shift in response to hydrogen peroxide (H(2)O(2)) and phorbol myristate acetate (PMA), respectively. | Tetradecanoylphorbol Acetate | v-raf-leukemia viral oncogene 1 | Mus musculus |
| 4 | Interestingly, H(2)O(2) produced synergistic increase of PMA-stimulated Raf-1 kinase activation after simultaneous treatment of PMA and H(2)O(2). | Tetradecanoylphorbol Acetate | v-raf-leukemia viral oncogene 1 | Mus musculus |
| 5 | Interestingly, H(2)O(2) produced synergistic increase of PMA-stimulated Raf-1 kinase activation after simultaneous treatment of PMA and H(2)O(2). | Tetradecanoylphorbol Acetate | v-raf-leukemia viral oncogene 1 | Mus musculus |
| 6 | Taken together, our data suggest that the synergistic activation of Raf-1 kinase in response to PMA and H(2)O(2) occurs via mechanisms that involve an interaction of Raf-1 kinase and PKC-epsilon, along with a transient phosphorylation of both Raf-1 kinase and PKC. | Tetradecanoylphorbol Acetate | v-raf-leukemia viral oncogene 1 | Mus musculus |
| 7 | Taken together, our data suggest that the synergistic activation of Raf-1 kinase in response to PMA and H(2)O(2) occurs via mechanisms that involve an interaction of Raf-1 kinase and PKC-epsilon, along with a transient phosphorylation of both Raf-1 kinase and PKC. | Tetradecanoylphorbol Acetate | v-raf-leukemia viral oncogene 1 | Mus musculus |
| 8 | Taken together, our data suggest that the synergistic activation of Raf-1 kinase in response to PMA and H(2)O(2) occurs via mechanisms that involve an interaction of Raf-1 kinase and PKC-epsilon, along with a transient phosphorylation of both Raf-1 kinase and PKC. | Tetradecanoylphorbol Acetate | v-raf-leukemia viral oncogene 1 | Mus musculus |