Title : Influence of ethylene-oxy spacer group on the activity of linezolid: synthesis of potent antibacterials possessing a thiocarbonyl group.

Pub. Date : 2003 Dec 1

PMID : 14622995






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1 The synthesis of linezolid analogues possessing the ethylene-oxy spacer group along with SAR studies with different heterocycles and preparation of some thiocarbonyl compounds possessing potent antibacterial property are presented. Linezolid sarcosine dehydrogenase Homo sapiens