Pub. Date : 2003 Oct
PMID : 14619584
6 Functional Relationships(s)Download |
Sentence | Compound Name | Protein Name | Organism |
| 1 | [Effects of cilazapril on the expression of vascular endothelial growth factor and intercellular adhesion molecule-1 in diabetic rat glomeruli]. | Cilazapril | intercellular adhesion molecule 1 | Rattus norvegicus |
| 2 | OBJECTIVE: To assess the effect of cilazapril, an angiotensin-converting enzyme inhibitor (ACEI), on the protection against diabetic nephropathy and on the expression of vascular endothelial growth factor (VEGF) and intercellular adhesion molecule-1 (ICAM-1) in diabetic rat glomeruli. | Cilazapril | intercellular adhesion molecule 1 | Rattus norvegicus |
| 3 | OBJECTIVE: To assess the effect of cilazapril, an angiotensin-converting enzyme inhibitor (ACEI), on the protection against diabetic nephropathy and on the expression of vascular endothelial growth factor (VEGF) and intercellular adhesion molecule-1 (ICAM-1) in diabetic rat glomeruli. | Cilazapril | intercellular adhesion molecule 1 | Rattus norvegicus |
| 4 | Cilazapril could reduce KW/BW, CCr and 24 hours urine protein count and significantly suppress the overexpression of VEGF and ICAM-1 in cilazapril treatment group after 8 weeks, compared with the DM model group(P < 0.05). | Cilazapril | intercellular adhesion molecule 1 | Rattus norvegicus |
| 5 | Cilazapril could reduce KW/BW, CCr and 24 hours urine protein count and significantly suppress the overexpression of VEGF and ICAM-1 in cilazapril treatment group after 8 weeks, compared with the DM model group(P < 0.05). | Cilazapril | intercellular adhesion molecule 1 | Rattus norvegicus |
| 6 | CONCLUSION: Cilazapril can suppress the overproduction of two cytokines, VEGF and ICAM-1, thus preventing the progression of diabetic nephropathy. | Cilazapril | intercellular adhesion molecule 1 | Rattus norvegicus |