Title : Effects of the mycotoxins alpha- and beta-zearalenol on regulation of progesterone synthesis in cultured granulosa cells from porcine ovaries.

Pub. Date : 2003 Nov-Dec

PMID : 14613819






1 Functional Relationships(s)
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1 The addition of alpha- or beta-ZOL (7.5, 15 and 30 microM) to cultures stimulated with FSH (0.01 microg) or forskolin (10 microM) reduced progesterone synthesis and the levels of p450scc and 3beta-HSD transcripts in a dose-dependent manner (P<0.05). Colforsin cytochrome P450 family 11 subfamily A member 1 Homo sapiens