Pub. Date : 2003 Nov 15
PMID : 14613719
3 Functional Relationships(s)Download |
Sentence | Compound Name | Protein Name | Organism |
| 1 | Wild-type (AhR(b)) mice treated with DMBA for 48 h exhibit a large loss in BM cellularity and disruption of marrow structure that is not seen for BP treatment. | 6,11-dimethylbenzo(b)naphtho(2,3-d)thiophene | aryl-hydrocarbon receptor | Mus musculus |
| 2 | In congenic mice with a low affinity AhR (AhR(d)), DMBA and BP are equally toxic to the BM whereas AhR(d) x CYP1B1-null mice are fully protected. | 6,11-dimethylbenzo(b)naphtho(2,3-d)thiophene | aryl-hydrocarbon receptor | Mus musculus |
| 3 | In congenic mice with a low affinity AhR (AhR(d)), DMBA and BP are equally toxic to the BM whereas AhR(d) x CYP1B1-null mice are fully protected. | 6,11-dimethylbenzo(b)naphtho(2,3-d)thiophene | aryl-hydrocarbon receptor | Mus musculus |