Pub. Date : 2003 Nov 15
PMID : 14613719
4 Functional Relationships(s)Download |
Sentence | Compound Name | Protein Name | Organism |
| 1 | Bone marrow cytotoxicity of benzo[a]pyrene is dependent on CYP1B1 but is diminished by Ah receptor-mediated induction of CYP1A1 in liver. | Benzo(a)pyrene | cytochrome P450, family 1, subfamily b, polypeptide 1 | Mus musculus |
| 2 | Benzo(a)pyrene (BP), a much more potent Ah receptor ligand, shows very different responses that nevertheless depend on CYP1B1. | Benzo(a)pyrene | cytochrome P450, family 1, subfamily b, polypeptide 1 | Mus musculus |
| 3 | Benzo(a)pyrene (BP), a much more potent Ah receptor ligand, shows very different responses that nevertheless depend on CYP1B1. | Benzo(a)pyrene | cytochrome P450, family 1, subfamily b, polypeptide 1 | Mus musculus |
| 4 | Thus, hepatic metabolism may prevent BP from reaching the BM, where it can be bioactivated by CYP1B1. | Benzo(a)pyrene | cytochrome P450, family 1, subfamily b, polypeptide 1 | Mus musculus |