Title : Bone marrow cytotoxicity of benzo[a]pyrene is dependent on CYP1B1 but is diminished by Ah receptor-mediated induction of CYP1A1 in liver.

Pub. Date : 2003 Nov 15

PMID : 14613719






2 Functional Relationships(s)
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1 Bone marrow cytotoxicity of benzo[a]pyrene is dependent on CYP1B1 but is diminished by Ah receptor-mediated induction of CYP1A1 in liver. Benzo(a)pyrene cytochrome P450, family 1, subfamily a, polypeptide 1 Mus musculus
2 In wild-type mice, BP treatment leads to a fivefold greater induction of hepatic CYP1A1 than that of DMBA treatment. Benzo(a)pyrene cytochrome P450, family 1, subfamily a, polypeptide 1 Mus musculus