Title : All hydrophobic HMG-CoA reductase inhibitors induce apoptotic death in rat pulmonary vein endothelial cells.

Pub. Date : 2003 Oct

PMID : 14612203






1 Functional Relationships(s)
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Compound Name
Protein Name
Organism
1 Lovastatin, simvastatin, atorvastatin, fluvastatin and cerivastatin, which are hydrophobic statins, markedly reduced cell viability associated with DNA fragmentation, DNA laddering and activation of caspase-3, suggesting apoptotic cell death. Lovastatin caspase 3 Rattus norvegicus