Title : Amino acids and insulin control autophagic proteolysis through different signaling pathways in relation to mTOR in isolated rat hepatocytes.

Pub. Date : 2004 Feb 27

PMID : 14610086






1 Functional Relationships(s)
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1 In isolated rat hepatocytes, both regulatory amino acids (RegAA) and insulin coordinately activated p70(S6k) phosphorylation, which was completely blocked by rapamycin, an mTOR inhibitor. Sirolimus mechanistic target of rapamycin kinase Rattus norvegicus