Title : 12-O-tetradecanoylphorbol-13-acetate may both potentiate and decrease the generation of apoptosis by the antileukemic agent arsenic trioxide in human promonocytic cells. Regulation by extracellular signal-regulated protein kinases and glutathione.

Pub. Date : 2004 Jan 30

PMID : 14610070






1 Functional Relationships(s)
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1 In addition TPA decreased the intracellular GSH content, caused ERK activation, and potentiated the As(2)O(3)-provoked activation of p38 and JNK. Tetradecanoylphorbol Acetate mitogen-activated protein kinase 14 Homo sapiens