Title : A new method of purifying fibrinogen with both biological and immunological activity from human plasma.

Pub. Date : 2003 Nov

PMID : 14606683






1 Functional Relationships(s)
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1 Using a combination of Cohn ethanol fractionation, virus inactivation, glycine and sodium chloride precipitation, and lysine-Sepharose affinity chromatography, a unique and rapid simplified method was developed to obtain highly purified fibrinogen for diagnostic use with both biological (Clauss method) and immunological (Jacobsson method) activity. Sepharose fibrinogen beta chain Homo sapiens