Pub. Date : 2003
PMID : 14597963
5 Functional Relationships(s)Download |
Sentence | Compound Name | Protein Name | Organism |
| 1 | Influence of CYP2C9 genotypes on the formation of a hepatotoxic metabolite of valproic acid in human liver microsomes. | Valproic Acid | cytochrome P450 family 2 subfamily C member 9 | Homo sapiens |
| 2 | The present study investigated the effect of cytochrome P450 2C9 (CYP2C9) genetic polymorphism on the biotransformation of valproic acid (VPA) to its hepatotoxic metabolite, 4-ene-VPA, and compared that to the formation of the inactive 4-OH-VPA and 5-OH-VPA. | Valproic Acid | cytochrome P450 family 2 subfamily C member 9 | Homo sapiens |
| 3 | The present study investigated the effect of cytochrome P450 2C9 (CYP2C9) genetic polymorphism on the biotransformation of valproic acid (VPA) to its hepatotoxic metabolite, 4-ene-VPA, and compared that to the formation of the inactive 4-OH-VPA and 5-OH-VPA. | Valproic Acid | cytochrome P450 family 2 subfamily C member 9 | Homo sapiens |
| 4 | The present study investigated the effect of cytochrome P450 2C9 (CYP2C9) genetic polymorphism on the biotransformation of valproic acid (VPA) to its hepatotoxic metabolite, 4-ene-VPA, and compared that to the formation of the inactive 4-OH-VPA and 5-OH-VPA. | Valproic Acid | cytochrome P450 family 2 subfamily C member 9 | Homo sapiens |
| 5 | The present study investigated the effect of cytochrome P450 2C9 (CYP2C9) genetic polymorphism on the biotransformation of valproic acid (VPA) to its hepatotoxic metabolite, 4-ene-VPA, and compared that to the formation of the inactive 4-OH-VPA and 5-OH-VPA. | Valproic Acid | cytochrome P450 family 2 subfamily C member 9 | Homo sapiens |