Pub. Date : 2003 Nov
PMID : 14597854
3 Functional Relationships(s)Download |
Sentence | Compound Name | Protein Name | Organism |
| 1 | Changes in iron availability can affect an important regulator of vascular tone, the endothelial nitric oxide synthase (eNOS), activated by a heme-dependent dimerization. | Heme | nitric oxide synthase 3 | Homo sapiens |
| 2 | Changes in iron availability can affect an important regulator of vascular tone, the endothelial nitric oxide synthase (eNOS), activated by a heme-dependent dimerization. | Heme | nitric oxide synthase 3 | Homo sapiens |
| 3 | CONCLUSIONS: The results of this study suggest a down-regulating effect of infectious and inflammatory stimuli on eNOS expression, both at the mRNA level and protein expression or stability and dimerization, enhanced by heme and iron shortage, and indicate eNOS as a possible link between infection and hypertension. | Heme | nitric oxide synthase 3 | Homo sapiens |