Pub. Date : 2003 Nov
PMID : 14585963
3 Functional Relationships(s)Download |
Sentence | Compound Name | Protein Name | Organism |
| 1 | We found that angiotensin II stimulates the tyrosine phosphorylation of PDK1 in vascular smooth muscle in a calcium- and c-Src-dependent manner. | Tyrosine | angiotensinogen | Homo sapiens |
| 2 | This critical function of Pyk2 is further supported by the observation that Pyk2 and tyrosine-phosphorylated PDK1 colocalize in focal adhesions after angiotensin II stimulation. | Tyrosine | angiotensinogen | Homo sapiens |
| 3 | Importantly, infection of smooth muscle cells with a Tyr9 mutant of PDK1 inhibits angiotensin II-induced tyrosine phosphorylation of paxillin and focal adhesion formation. | Tyrosine | angiotensinogen | Homo sapiens |