Title : c-Myc overexpression sensitises colon cancer cells to camptothecin-induced apoptosis.

Pub. Date : 2003 Nov 3

PMID : 14583781






5 Functional Relationships(s)
Download
Sentence
Compound Name
Protein Name
Organism
1 Both camptothecin exposure and c-Myc overexpression in LoVo cells resulted in elevation of p53 protein levels, suggesting a role of p53 in the c-Myc-imposed sensitisation to the apoptotic effects of camptothecin. Camptothecin tumor protein p53 Homo sapiens
2 Both camptothecin exposure and c-Myc overexpression in LoVo cells resulted in elevation of p53 protein levels, suggesting a role of p53 in the c-Myc-imposed sensitisation to the apoptotic effects of camptothecin. Camptothecin tumor protein p53 Homo sapiens
3 Both camptothecin exposure and c-Myc overexpression in LoVo cells resulted in elevation of p53 protein levels, suggesting a role of p53 in the c-Myc-imposed sensitisation to the apoptotic effects of camptothecin. Camptothecin tumor protein p53 Homo sapiens
4 Both camptothecin exposure and c-Myc overexpression in LoVo cells resulted in elevation of p53 protein levels, suggesting a role of p53 in the c-Myc-imposed sensitisation to the apoptotic effects of camptothecin. Camptothecin tumor protein p53 Homo sapiens
5 This was confirmed by the ability of PFT-alpha, a specific inhibitor of p53, to attenuate camptothecin-induced apoptosis. Camptothecin tumor protein p53 Homo sapiens