Title : Expression of the angiogenic factor thymidine phosphorylase in THP-1 monocytes: induction by autocrine tumor necrosis factor-alpha and inhibition by aspirin.

Pub. Date : 2003 Nov

PMID : 14573775






3 Functional Relationships(s)
Download
Sentence
Compound Name
Protein Name
Organism
1 An alternative mechanism by which aspirin inhibits gene expression is the modulation of the transcription factor NFkappaB, and the TNFalpha-induced increase in TP mRNA was blocked by a cell-permeable NFkappaB inhibitory peptide. Aspirin nuclear factor kappa B subunit 1 Homo sapiens
2 An alternative mechanism by which aspirin inhibits gene expression is the modulation of the transcription factor NFkappaB, and the TNFalpha-induced increase in TP mRNA was blocked by a cell-permeable NFkappaB inhibitory peptide. Aspirin nuclear factor kappa B subunit 1 Homo sapiens
3 Furthermore, TNFalpha increased and aspirin (but not indomethacin) decreased NFkappaB DNA-binding activity in THP-1 cells. Aspirin nuclear factor kappa B subunit 1 Homo sapiens