Pub. Date : 2003 Nov
PMID : 14572862
6 Functional Relationships(s)Download |
Sentence | Compound Name | Protein Name | Organism |
1 | Proline analogue of melphalan as a prodrug susceptible to the action of prolidase in breast cancer MDA-MB 231 cells. | Proline | peptidase D | Homo sapiens |
2 | Proline analogue of melphalan (Mel-pro) was synthesized as a prodrug susceptible to the action of ubiquitously distributed, cytosolic imidodipeptidase-prolidase [E.C.3.4.13.9]. | Proline | peptidase D | Homo sapiens |
3 | Conjugation of melphalan (Mel) with proline (Pro) through imido-bond resulted in formation of a good substrate for prolidase. | Proline | peptidase D | Homo sapiens |
4 | Conjugation of melphalan (Mel) with proline (Pro) through imido-bond resulted in formation of a good substrate for prolidase. | Proline | peptidase D | Homo sapiens |
5 | Cytosolic location of prolidase in neoplastic cell suggests that proline analogue of melphalan (Mel-pro) may serve as a prolidase convertible prodrug. | Proline | peptidase D | Homo sapiens |
6 | Cytosolic location of prolidase in neoplastic cell suggests that proline analogue of melphalan (Mel-pro) may serve as a prolidase convertible prodrug. | Proline | peptidase D | Homo sapiens |