Title : Glutamine stimulates argininosuccinate synthetase gene expression through cytosolic O-glycosylation of Sp1 in Caco-2 cells.

Pub. Date : 2003 Dec 26

PMID : 14570901






1 Functional Relationships(s)
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1 Taken together, the results clearly demonstrate that the metabolism of glutamine through the hexosamine pathway leads to the cytosolic O-glycosylation of Sp1, which, in turn, translocates into nucleus and stimulates the ASS gene transcription. Hexosamines argininosuccinate synthase 1 Homo sapiens