Pub. Date : 2003 Nov
PMID : 14570773
1 Functional Relationships(s)Download |
Sentence | Compound Name | Protein Name | Organism |
| 1 | In contrast to microsomes, the oxidation of rofecoxib to 5-hydroxyrofecoxib by S9 fractions followed two pathways, one NADPH-dependent and one NAD+-dependent (non-cytochrome P450), with the latter accounting for about 40% of total activity. | 5-hydroxyrofecoxib | cytochrome P450 family 4 subfamily F member 3 | Homo sapiens |