Title : Interactions between the nitric oxide and prostaglandin E2 biosynthetic pathways in human amnion-like WISH cells.

Pub. Date : 2003 Oct

PMID : 14568676






1 Functional Relationships(s)
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1 In particular, we demonstrate that exogenous NO inhibits PGE2 release evoked by IL-1beta whereas high levels of the prostanoid, in the presence of proinflammatory agents, exert a negative feed-back control on iNOS mRNA expression, possibly through a cAMP-dependent mechanism. Cyclic AMP nitric oxide synthase 2 Homo sapiens