Title : Potent mechanism-based inhibition of human CYP2B6 by clopidogrel and ticlopidine.

Pub. Date : 2004 Jan

PMID : 14563790






1 Functional Relationships(s)
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1 Inhibition of CYP2B6 was time- and concentration-dependent, and as shown by dialysis experiments, it was irreversible and dependent on NADPH, suggesting a mechanism-based mode of action. NADP cytochrome P450 family 2 subfamily B member 6 Homo sapiens