Title : AKT/protein kinase B regulation of BCL family members during oxysterol-induced apoptosis.

Pub. Date : 2004 Jan 9

PMID : 14559920






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1 In this study, we demonstrate that, in the murine macrophage-like cell line P388D1, oxysterols (25-hydroxycholesterol and 7-ketocholesterol) induced the degradation of the prosurvival protein kinase AKT (protein kinase B). 7-ketocholesterol thymoma viral proto-oncogene 1 Mus musculus