Pub. Date : 2003 Oct
PMID : 14559676
2 Functional Relationships(s)Download |
Sentence | Compound Name | Protein Name | Organism |
1 | As2O3-induced apoptosis was accompanied by down-regulation of Bcl-xL protein expression and activation of apoptosis protein caspase-3, as identified by Western blotting. | Arsenic Trioxide | BCL2 like 1 | Homo sapiens |
2 | CONCLUSION: As2O3 exerts apoptosis-inducing effects on human Burkitt lymphoma cells through down-regulation of Bcl-xL protein expression and activation of apoptosis protein caspase-3, and may serve as a candidate therapeutic agent against malignant lymphoma for both systemic and local therapies. | Arsenic Trioxide | BCL2 like 1 | Homo sapiens |