Title : [From heparin to synthetic antithrombotic oligosaccharides].

Pub. Date : 2003

PMID : 14556453






2 Functional Relationships(s)
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1 In the early eighties, following breakthroughs in oligosaccharide chemistry, we achieved the total chemical synthesis of pentasaccharides related to the antithrombin-binding domain in heparin. Oligosaccharides serpin family C member 1 Homo sapiens
2 In a further step, we have designed and synthesised oligosaccharides (pentadeca--to eicosasaccharides), comprising an antithrombin binding domain prolonged by a thrombin binding domain. Oligosaccharides serpin family C member 1 Homo sapiens