Pub. Date : 2003 Oct
PMID : 14534154
7 Functional Relationships(s)Download |
Sentence | Compound Name | Protein Name | Organism |
| 1 | Capsaicin induces calcitonin gene-related peptide (CGRP) release when VR1 receptors are activated, and this can be reversed by both the VR1 receptor antagonist capsazepine and the CGRP blocker alphaCGRP8-37 in vitro. | Capsaicin | calcitonin related polypeptide alpha | Homo sapiens |
| 2 | Capsaicin induces calcitonin gene-related peptide (CGRP) release when VR1 receptors are activated, and this can be reversed by both the VR1 receptor antagonist capsazepine and the CGRP blocker alphaCGRP8-37 in vitro. | Capsaicin | calcitonin related polypeptide alpha | Homo sapiens |
| 3 | Capsaicin induces calcitonin gene-related peptide (CGRP) release when VR1 receptors are activated, and this can be reversed by both the VR1 receptor antagonist capsazepine and the CGRP blocker alphaCGRP8-37 in vitro. | Capsaicin | calcitonin related polypeptide alpha | Homo sapiens |
| 4 | We also looked at the effect of the CGRP blocker alphaCGRP8-37 (300 microg x kg-1) on capsaicin-induced dilation so that we could see if the results found in vitro could also be found in vivo. | Capsaicin | calcitonin related polypeptide alpha | Homo sapiens |
| 5 | AlphaCGRP8-37 also inhibited the capsaicin-induced dilation (t5=7.4, P<0.05) probably inhibiting the action of released CGRP at the CGRP receptor. | Capsaicin | calcitonin related polypeptide alpha | Homo sapiens |
| 6 | AlphaCGRP8-37 also inhibited the capsaicin-induced dilation (t5=7.4, P<0.05) probably inhibiting the action of released CGRP at the CGRP receptor. | Capsaicin | calcitonin related polypeptide alpha | Homo sapiens |
| 7 | The study demonstrates that capsaicin can repeatedly induce dural vessel dilation in vivo, presumably through inducing CGRP release from trigeminal sensory nerve fibres, while C-fibres may have been desensitised. | Capsaicin | calcitonin related polypeptide alpha | Homo sapiens |