Title : Analysis of transmembrane segment 7 of the dipeptide transporter hPepT1 by cysteine-scanning mutagenesis.

Pub. Date : 2003 Dec 19

PMID : 14532279






2 Functional Relationships(s)
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1 Out of the remaining 19 transporters, three (F293C-, L296C-, and F297C-hPepT1) showed negligible glycyl-sarcosine (gly-sar) uptake activity and may play an important role in defining the overall hPepT1 structure. Glycine solute carrier family 15 member 1 Homo sapiens
2 MTSET modification of R282C-hPepT1 resulted in a significant increase in gly-sar uptake. Glycine solute carrier family 15 member 1 Homo sapiens