Pub. Date : 2003 Nov 1
PMID : 14529784
3 Functional Relationships(s)Download |
Sentence | Compound Name | Protein Name | Organism |
| 1 | This study examines whether lipid A may directly modulate the radioresponse of tumor cells by activating inducible nitric oxide synthase (iNOS) or cyclooxygenase-2 (COX-2) through nuclear factor-kappaB (NF-kappaB) signaling. | Lipid A | nitric oxide synthase 2, inducible | Mus musculus |
| 2 | This study examines whether lipid A may directly modulate the radioresponse of tumor cells by activating inducible nitric oxide synthase (iNOS) or cyclooxygenase-2 (COX-2) through nuclear factor-kappaB (NF-kappaB) signaling. | Lipid A | nitric oxide synthase 2, inducible | Mus musculus |
| 3 | RESULTS: Lipid A dose-dependently increased the expression and activity of iNOS with a maximal effect at plasma achievable concentrations of 3-30 micro g/mL. | Lipid A | nitric oxide synthase 2, inducible | Mus musculus |