Pub. Date : 2003
PMID : 14526176
1 Functional Relationships(s)Download |
Sentence | Compound Name | Protein Name | Organism |
| 1 | SCA7 has a number of features in common with other diseases with polyglutamine expansions: (i) the appearance of clinical symptoms above a threshold number of CAG repeats (>35); (ii) a correlation between the size of the expansion and the rate of progression of the disease: the larger the repeat, the faster the progression; (iii) instability of the repeat sequence (approximately 12 CAG/transmission) that accounts for the marked anticipation of approximately 20 years/generation. | polyglutamine | ataxin 7 | Homo sapiens |